Any dose of etizolam with noticeable effects taken on a long enough timeline can form a mental and physical dependence on the drug.

It causes shock, bradycardia, or cardiac arrest when used with alcohol or other central nervous depressants.

Systolic and diastolic pressure decreased significantly in 13 patients (72.2%) and 10 patients (55.5%), respectively.

Based on the kinetic characteristics of the parent drug and its metabolite, etizolam can be regarded as a short-acting benzodiazepine.